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Table 15 Cognitive behavioural therapy for Anorexia Nervosa

From: Canadian practice guidelines for the treatment of children and adolescents with eating disorders

Certainty assessmentImpactCertaintyImportance
№ of studiesStudy designRisk of biasInconsistencyIndirectnessImprecisionOther considerations
Weight (assessed with: BMI), Psychological symptoms (EDE)
 1randomised trialsnot seriousnot seriousnot seriousnot seriousnoneRCT with 11 adolescents and young adults in CBT group compared to 11 in the Behavioural Family Therapy group (age range 13–23). There were no significant differences in terms of weight.
HIGH
CRITICAL
not seriousnot seriousnot seriousnot seriousnoneNo differences seen in the eating psychopathology on the EDE between treatment groups.
HIGH
CRITICAL
Weight (assessed with: kg), psychological symptoms with EDE
 1Case Seriesvery serious a,bnot seriousnot seriousnot seriousstrong associationThis was a large case series of 49 adolescents age 13 to 17 years, all female. 40 sessions weekly for 45 min. Weight was significantly increased by an average of 8.6 kg comparing pre to post weight.
VERY LOW
CRITICAL
very serious a,bnot seriousnot seriousnot seriousstrong associationEDE scores were substantially decreased by a score of 2.03 (range 0–6) indicating psychological symptoms were much improved from pre to post treatment.
VERY LOW
CRITICAL
Weight (assessed with: kg), psychological symptoms
 8Case Reportsvery serious a,bnot seriousnot seriousnot seriousnone8 case reports describing 8 adolescents (7 females, 1 male) with AN treated with CBT. One case had comorbid OCD. Weight improved with treatment. Age range 11.5 to 17 years.
VERY LOW
CRITICAL
very serious a,bnot seriousnot seriousnot seriousnoneImproved EDE scores and EDI scores as well as improved eating behaviours in terms of a reduction in restricted eating.
VERY LOW
CRITICAL
  1. Explanations
  2. ano randomization
  3. bno control condition
  4. Bibliography:
  5. RCT - Ball 2004 [24]
  6. Case Series - Dalle Grave 2013 [96]
  7. Case Reports - Cowdrey 2016 [97], Cooper 1984 [98], Martin-Murcia 2011 [99], Heffner 2002 [100], Scrignar 1971 [101], Fundudis 1986 [102], Ollendick 1979 [103], Wildes 2011 [104]