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Table 9 Multi family therapy for eating disorders

From: Canadian practice guidelines for the treatment of children and adolescents with eating disorders

Certainty assessmentImpactCertaintyImportance
DEStudy designRisk of biasInconsistencyIndirectnessImprecisionOther considerations
Good Outcome at End of Treatment (assessed with: Morgan Russell Scale), Psychological Symptoms (EDE)
 1randomised trialsnot seriousnot seriousnot seriousnot seriousnoneRCT (n = 169) of adolescents with AN aged 11–18 comparing MFT to FBT (91% female). 65/86 (75.6%) good outcome at end of treatment in MFT versus 48/83 (57.8%) in the FBT group - significant difference.
No differences between groups seen on the EDE. Both groups improved over time on the EDE.

HIGH
CRITICAL
not seriousnot seriousnot seriousnot seriousnoneNo differences between groups seen on the EDE. Both groups improved over time on the EDE.
HIGH
CRITICAL
Weight (assessed with: Percent ideal body weight)
 1Case controlserious anot seriousnot seriousnot seriousnoneRetrospective case control study looking at MFT versus TAU for AN. 50 female adolescents aged 11–18 were included (25 in MFT group and 25 in TAU group). Those in MFT restored weight to a higher percentage (99.6% vs. 95.4%).
VERY LOW
CRITICAL
Weight (assessed with: kg and BMI) Psychological Symptoms (assessed with: EDE, EDI)
 4Case Seriesvery serious a,bnot seriousnot seriousnot seriousnoneFour studies without a control condition. Total n = 142 adolescents (5 males, 137 females), Diagnoses were mixed including AN, EDNOS and BN. Significant improvements in weight were reported.
VERY LOW
CRITICAL
very serious a,bnot seriousnot seriousnot seriousnoneImprovements in psychological symptoms were seen pre to post MFT.
In a case series of 10 adolescents aged 13 to 18 years, EDE scores decreased from 4.31 to 3.41 (cohen’s d 0.82).

VERY LOW
CRITICAL
  1. ano randomization
  2. bno control condition
  3. Bibliography:
  4. RCT – Eisler 2016 [76]
  5. Case control - Gabel 2014 [77]
  6. Case Series - Gelin 2015 [80], Hollesen 2013 [78], Salaminiou 2017 [79], Stewart 2015 [81]